The guanine content in specimens of house dust collected in the living quarters of healthy persons and of patients with atopic bronchial asthma
Dotsenko, E.A.; Prishchepa, I.M.; Novikov, D.K.; Dotsenko, M.L.; Efremenko, I.I.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 6: 70-73
1997
ISSN/ISBN: 0372-9311 PMID: 9460872 Document Number: 472604
The content of insoluble guanine fractions originating from micromites in specimens of house dust, collected in the dwellings of 15 healthy persons with no signs of allergy and 64 patients with atopic bronchial asthma (ABA), was studied. The content of these fractions in house dust in the dwellings of ABA patients was significantly higher than that in house dust in the dwellings of healthy persons (0.76 +/- 0.119 in comparison 0.31 +/- 0.040, p < 0.05). A high content of guanine was detected in house dust of the dwellings of 74.1% of ABA patients and 33.3% of healthy persons, which was indicative of the importance of mite contamination in the formation of ABA.