Current orientation about congenital Cytomegalovirus infection
Carillo, C.; Cerenzia, G.; Serrao, L.; Niccoli, V.S.
La Clinica Terapeutica 148(10): 437-442
1997
ISSN/ISBN: 0009-9074 PMID: 9470305 Document Number: 472523
The CMV infection in pregnancy make serious problems about the diagnosis and the fetal prognosis. Infact primary infection by CMV is loaded by an high risk of congenital infection and the presence of antibodies IgG do not prevent a possible reinfection. Furthermore, the latent presence in the host of CMV induces his reactivation when the immunosorveillance decreases during pregnancy. The consequences of primary infection are well shown during pregnancy and they are very grave, but also the reactivations induce especially neurological consequences, that however are shown only after some months from delivery. Therefore in consideration of the prognosis and the poor therapeutics, the management in these cases is essentially to give minute details to the mother about all the consequences for the fetus without to exclude, because of serious sequels, so that just she can to decide the future of her pregnancy.