Suppression of immunological response in a newborn with congenital cytomegalovirus infection: diagnostic difficulties
Furmaga-Jabłońska, W.; Korczowski, B.; Maksymiuk, B.
Pediatria Polska 71(4): 351-357
1996
ISSN/ISBN: 0031-3939 PMID: 8975225 Document Number: 457499
A newborn with symptoms of congenital cytomegalovirus infection (interuterine dystrophy, thrombocytopenia, leukopenia, hepatosplenomegaly, chronic pneumonia, pleocytosis in CSF) is described in whom tests for specific anti- CMV-IgM antibodies were negative. Changes typical for cytomegaloviral infection were found on autopsy. The authors discuss the difficulties in interpreting various serologic tests (CFT, anti-CMV IgM) in congenital infections, suggesting the necessity of introducing new diagnostic methods for better diagnosis and treatment.