The role of blockage of various M-cholinoreceptor subtypes in induction of tachycardia in rats
Kosmachev, A.B.; Lychakov, A.V.; Saunkina, I.A.; Fil'ko, O.A.; Chigareva, S.M.
Eksperimental'naia i Klinicheskaia Farmakologiia 60(5): 44-46
1997
ISSN/ISBN: 0869-2092 PMID: 9483405 Document Number: 472408
The mechanism of the effect of M-cholinoblockers on the heart rate was analysed. It is suggested on the basis of this analysis that tachycardia induced in reats by muscarinic antagonists was caused by blockade of ther central M1-cholinoceptors which is accompanied with increase in the tone of the sympathetic branch of the autonomic nervous system.
Document emailed within 1 workday
Related Documents
Fenichel, P.; Grimaldi, M.; Greck, T.; Benoit, B.; Fiorentini, M.; Tran, D.K.; Gillet, J.Y.; Harter, M. 1986: Hypophyseal blockage by a gonadorelin analogue, D-Trp6-LHRH retard, to improve induction of ovulation Presse Medicale 15(43): 2167Klinger, W.; Elger, J.; Franke, H.; Reinicke, C.; Traeger, A.; Volkmann, H.; Wahrenberg, I.; Ankermann, H. 1970: Studies on the mechanism of enzyme induction. XV. Induction pattern and submicroscopic changes in the liver following application of phenylbutazone in rats of different ages Acta Biologica et Medica Germanica 24(4): 463-482
Kieny, J.R.; Roul, G.; Sachs, D.; Mossard, J.M.; Bareiss, P.; Sacrez, A. 1991: Induction of ventricular tachycardia by esophageal stimulation. Apropos of 2 cases Archives des Maladies du Coeur et des Vaisseaux 84(11): 1587-1590
Imaida, K.; Uneyama, C.; Ogasawara, H.; Hayashi, S.; Fukuhara, K.; Miyata, N.; Takahashi, M. 1992: Induction of colon adenocarcinomas in CD rats and lung adenomas in ICR mice by 6-nitrochrysene: comparison of carcinogenicity and aryl hydrocarbon hydroxylase induction in the target organs of each species Cancer Research 52(6): 1542-1545
Jaller Char, J.J.; Jaller, J.A.; Waibel, J.S.; Bhanusali, D.G.; Bhanusali, N. 2018: The Role of IL-17 in the Human Immune System and its Blockage as a Treatment of Rheumatoid Arthritis, Ankylosing Spondylitis, and Psoriatic Arthritis Journal of Drugs in Dermatology: Jdd 17(5): 539-542
Rogers, A.E.; Herndon, B.J.; Newberne, P.M. 1973: Induction by dimethylhydrazine of intestinal carcinoma in normal rats and rats fed high or low levels of vitamin A Cancer Research 33(5): 1003-1009
Vorob'ev, V.V.; Akhmetova, E.R.; Kovalev, G.I. 1999: The participation of the 5-HT1 and 5-HT2 subtypes of the serotonin receptors in the formation of the frequency component in the EEG of non-narcotized rats Eksperimental'naia i Klinicheskaia Farmakologiia 62(1): 15-18
Di Renzo, G.; Marino, A. 1990: Serotonin receptor subtypes. Considerations on their physiological role and therapeutic prospects La Clinica Terapeutica 133(1): 3-7
Abe, T.; Morgan, D.A.; Gutterman, D.D. 1997: Role of adenosine receptor subtypes in neural stunning of sympathetic coronary innervation American Journal of Physiology 272(1 Pt 2): H25-H34
Wei, J.; Milici, A.; Buccafusco, J.J. 1995: Alterations in the expression of the genes encoding specific muscarinic receptor subtypes in the hypothalamus of spontaneously hypertensive rats Circulation Research 76(1): 142-147
Burlakov, G.V. 1989: Pharmacologic properties of cholinoreceptor antibodies Biulleten' Eksperimental'noi Biologii i Meditsiny 108(9): 320-322
Speranskaià, T.A.; Mitropolitanskaià, R.L. 1971: Effect of streptomycin on the reaction of acetylcholine with a cholinoreceptor in vitro Antibiotiki 16(3): 262-265
Campbell, R.M.; Strieper, M.J.; Frias, P.A. 2004: The role of radiofrequency ablation for pediatric supraventricular tachycardia Minerva Pediatrica 56(1): 63-72
Iljin, V.I.; Bregestovski, P.D. 1977: Chemical nature of functional cholinoreceptor groups of Lymnaea stagnalis neurons Acta Physiologica Academiae Scientiarum Hungaricae 49(3-4): 221-230
González, R.; Fajuri, A.; Arriagada, C.; Marchesse, M.; Serrat, H. 1989: Idiopathic recurrent ventricular tachycardia: role of verapamil in its treatment Revista Medica de Chile 117(4): 440-444
Ognibene, A.; Ciniglio, R.; Greifenstein, A.; Jarjoura, D.; Cugino, A.; Blend, D.; Whittier, F. 1994: Ventricular tachycardia in acute myocardial infarction: the role of hypophosphatemia Southern Medical Journal 87(1): 65-69
Sattar, M.A.; Johns, E.J. 1996: Alpha-1 adrenoceptor subtypes involved in mediating adrenergically induced antinatriuresis and antidiuresis in two kidney, one clip Goldblatt and deoxycorticosterone acetate-salt hypertensive rats Journal of Pharmacology and Experimental Therapeutics 277(1): 245-252
Suzuki, E.; Tsujimoto, G.; Tamura, K.; Hashimoto, K. 1990: Two pharmacologically distinct alpha 1-adrenoceptor subtypes in the contraction of rabbit aorta: each subtype couples with a different Ca2+ signalling mechanism and plays a different physiological role Molecular Pharmacology 38(5): 725-736
Siutkina, E.V. 1985: Effect of cholinoreceptor and beta-adrenoreceptor blockade on the variability of cardiac rhythm in rat fetuses Vestnik Akademii Meditsinskikh Nauk SSSR 6: 31-35
Gilbert, J.C.; Weissenburger, J.; Rozensztajn, L.; Jaillon, P.; Cheymol, G. 1975: Pharmacodynamic study of supraventricular tachycardia in the human. Beneficial role of atropine Therapie 30(6): 809-814