Pharmacologic properties of cholinoreceptor antibodies
Burlakov, G.V.
Biulleten' Eksperimental'noi Biologii i Meditsiny 108(9): 320-322
1989
ISSN/ISBN: 0365-9615 PMID: 2611390 Document Number: 339981
The study of pharmacological properties of cholinoreceptor antibodies is of definite interest due to the possibility of simulation of some myasthenic conditions. In 1986 the authors obtained antibodies by means of immunization of rabbits with antigenic material from skeletal muscles of the extremities of Balb/c mice. It was shown that incubation of the muscle with cholinoreceptor antibodies decreased its contraction under the effect of various concentrations of acetylcholine.