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Long-term follow-up by coronary angiography in a patient with heterozygous familial hypercholesterolemia: a case report

Saku, K.; Takeda, Y.; Shirai, K.; Nii, T.; Ohta, T.; Arakawa, K.

Journal of Cardiology 30(3): 137-142

1997

ISSN/ISBN: 0914-5087
PMID: 9309510
Document Number: 471855
A 47-year-old man with heterozygous familial hypercholesterolemia was followed up by coronary angiography for 9 years. During these 9 years, he experienced inferior myocardial infarction twice, at segment 1 of the right coronary artery. A coronary atherosclerotic lesion (50% stenosis) was also present at segment 6 of the left anterior descending coronary artery. This lesion remained unchanged for the first 7 years, but then rapidly progressed to 90% stenosis in the 8th year. While the rate of the progression of coronary atherosclerosis is generally unpredictable, it may progress rapidly in this case of heterozygous familial hypercholesterolemia.

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