Disorders developing under combined exposure to ionizing radiation and stress
Fedorov, V.I.
Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 1: 31-33
1997
ISSN/ISBN: 0031-2991 PMID: 9157380 Document Number: 471545
The combined influence of gamma-radiation in a dose of 1 Gy and restriction stress was studied in experiments on 62 rats. The severity of gastric mucosal erosive and ulcerative lesions, the rate of lipid peroxidation, and hepatic homogenate heat generation were determined by microcalorimetry. The developing disorders were corrected by administering sodium succinate. Animal radiation resulted in modified stress-induced gastric mucosal lesions which appeared as increases in the total number of ulcerations. The use of sodium succinate was followed by less severity of erosive and ulcerative gastric mucosal lesions, lower levels of malonic dialdehyde, and decreased hepatic homogenate heat elaboration.