Immunocorrective action of tuftsin during exposure to ionizing radiation
Val'dman, A.V.; Ratnikov, V.I.; Makarova, N.V.; Kozlovskaia, M.M.
Biulleten' Eksperimental'noi Biologii i Meditsiny 95(5): 34-35
1983
ISSN/ISBN: 0365-9615 PMID: 6687815 Document Number: 211589
The effect of the tetrapeptide tuftcin (Thr-Lys-Pro-Arg) on the humoral immune response in CBA mice exposed to sublethal irradiation in a dose of 450 sGy was studied. The drug was injected intraperitoneally for 5 days before (series I) or after (series II) radiation exposure. It has been shown that taftcin has no protective action but decreases considerably the immune response lowering due to radiation.