Combination chemotherapy with total or subtotal lymphatic irradiation in the treatment of lymphogranulomatosis, stage IIIA or IIIB (based on five- and ten-year results)
Kanaev, S.V.; Gershanovich, M.L.; Malinin, A.P.
Voprosy Onkologii 43(1): 32-38
1997
ISSN/ISBN: 0507-3758 PMID: 9133084 Document Number: 469993
High rates of overall and recurrence-free 5- and 10-year survival were recorded in 561 patients with Hodgkin's disease (stage IIIA-IIIAE and IIIB-IIIBE) after combination therapy using 2-4 cycles of MOPP, MOPP/ABV, COPP, DOPP or DOPP/ABV polychemotherapy, with radiation treatment being reduced to subtotal irradiation of lymph collectors. Total 5- and 10-year survival for stage IIIA was 96.8 and 91.5 and recurrence-free survival-81.2 and 81.2%, respectively: for stage IIIB-90.7; 83.2 and 68.6; 56.6%, respectively.