Pulmonary infiltrates with masto- and lymphocytosis in BALF associated with arechine
Jedynak, U.; Ciezarek, M.; Kopiński, P.
Polish Journal of Pathology Official Journal of the Polish Society of Pathologists 48(1): 63-67
1997
ISSN/ISBN: 1233-9687 PMID: 9200963 Document Number: 469666
Pulmonary infiltrates developed in a 40-year-old man while receiving arechine. The hyperplasia of mast cells, hyperlymphocytosis, a predominance of cytotoxic T-cells of the CD8 type with the very low CD4/CD8 ratio in BAL were observed. The chest roentgenogram findings resolved within a month after discontinuing arechine therapy. A hypersensitivity reaction with the onset of lung fibrosis due to arechine seemed to be the likely cause.