Serotonin-reactive neurons of the neocortex
Otellin, V.A.; Korzhevskiĭ, D.E.
Morfologiia 110(4): 23-25
1996
ISSN/ISBN: 1026-3543 PMID: 8983500 Document Number: 468071
In the course of study performed on Wistar line rats using light and electron microscopy it was found that brain serotoninergic system damage by the selective neurotoxin of 5,7 dihydroxytryptamine leads to degenerative changes in certain pyramidal neurons of the motor cortex superficial layers. Deep layers pyramid neurons acquire the signs of functional activity increase with the appearance of intranuclear inclusions. The results obtained are discussed with taking to consideration the impact of serotoninergic system damage on the neuropsychic diseases pathogenesis.