DNA-fingerprinting and tuberculosis
Bauer, J.O.; Clementsen, P.S.; Faurschou, P.
Ugeskrift for Laeger 158(8): 1084-1085
1996
ISSN/ISBN: 0041-5782 PMID: 8638343 Document Number: 467613
DNA-fingerprinting or RFLP (Restriction Fragment Length Polymorphism) is a molecular biological technique which allows differentiation between tuberculosis strains. The technique is based on the occurrence of repetitive elements in the mycobacterial genome and is a powerful tool in epidemiological studies. DNA-fingerprinting is also of value in tracking the spread of infection in patients with tuberculosis. The latter is illustrated in two case stories.