Neuroendocrine carcinoma of the larynx
Hartley, C.; Birzgalis, A.R.; Lyons, T.J.; Farrington, W.T.
Journal of the Royal College of Surgeons of Edinburgh 41(5): 333-335
1996
ISSN/ISBN: 0035-8835 PMID: 8908962 Document Number: 466789
Neuroendocrine carcinomas (NEC) of the larynx are rare. The key to diagnosis is therefore an increased awareness of such lesions amongst otolaryngologists and pathologists. A precise histological diagnosis is crucial, as the management is different for each NEC sub-type. Advances in immunohistochemistry have been a great help in this respect. We report a typical case of large cell NEC (atypical carcinoid) and highlight the clinical pointers to the histological diagnosis.