In vivo bioavailability predictions from perfused intestine studies
Soria, I.; Zimmerman, C.L.
International Journal of Clinical Pharmacology and Therapeutics 34(2): 90-91
1996
ISSN/ISBN: 0946-1965 PMID: 8929754 Document Number: 466637
Document emailed within 1 workday
Related Documents
Grimelius, L.; Johnson, L. 1973: Morphological and fluorescence-histochemical studies on isolated, homologously perfused small intestine Acta Chirurgica Scandinavica 139(3): 286-292Hirayama, H.; Pang, K.S. 1990: First-pass metabolism of gentisamide: influence of intestinal metabolism on hepatic formation of conjugates. Studies in the once-through vascularly perfused rat intestine-liver preparation Drug Metabolism and Disposition: the Biological Fate of Chemicals 18(5): 580-587
Neale, T.J.; Couser, W.G.; Salant, D.J.; Lowenstein, L.M.; Wilson, C.B. 1982: Specific uptake of Heymann's nephritic kidney eluate by rat kidney: studies in vivo and in isolated perfused kidneys Laboratory Investigation; a Journal of Technical Methods and Pathology 46(4): 450-453
Grandjean, C.; Garcia, H. 1975: Studies on liver regeneration. Deoxyribonucleic acid synthesis in the isolated perfused liver after in vitro and in vivo partial hepatectomy Laboratory Investigation; a Journal of Technical Methods and Pathology 32(4): 552-554
Winton, D.J.; Gooderham, N.J.; Boobis, A.R.; Davies, D.S.; Ponder, B.A. 1990: Mutagenesis of mouse intestine in vivo using the Dlb-1 specific locus test: studies with 1,2-dimethylhydrazine, dimethylnitrosamine, and the dietary mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline Cancer Research 50(24): 7992-7996
Lawrenz, A.; Eglit, S.; Kroker, R. 1992: The metabolism of albendazole in the isolated perfused intestine of rats Deutsche Tierärztliche Wochenschrift 99(10): 416-418
Pang, K.S.; Yuen, V.; Fayz, S.; te Koppele, J.M.; Mulder, G.J. 1986: Absorption and metabolism of acetaminophen by the in situ perfused rat small intestine preparation Drug Metabolism and Disposition: the Biological Fate of Chemicals 14(1): 102-111
Tygstrup, N.; Funding, J.; Juul-Nielsen, J.; Keiding, S.; Koudahl, G.; Ramsöe, K.; Winkler, K. 1971: The function of the isolated perfused and the in vivo pig liver Scandinavian Journal of Gastroenterology. Suppl 9: 131-138
Pang, K.S.; Cherry, W.F.; Ulm, E.H. 1985: Disposition of enalapril in the perfused rat intestine-liver preparation: absorption, metabolism and first-pass effect Journal of Pharmacology and Experimental Therapeutics 233(3): 788-795
Gielsdorf, W.; Nieder, M.; Molz, K.H.; Jaeger, H.; Haerlin, R.; Radtke, H.W. 1986: The pharmacokinetics and bioavailability of urapidil. in vitro/in vivo correlations of different experimental formulations Arzneimittel-Forschung 36(8): 1265-1267
Suthisisang, C.; Payakachat, N.; Chulavatnatol, S.; Towanabut, S. 1998: Bioavailability of phenytoin sodium capsules available in Thailand. Part II: in vivo study Journal of the Medical Association of Thailand 81(1): 64-70
Terhaag, B.; Donath, F.; Le Petit, G.; Feller, K. 1986: The absolute and relative bioavailability of dipyridamole from different preparations and the in vitro-in vivo comparison International Journal of Clinical Pharmacology Therapy and Toxicology 24(6): 298-302
Halsas, M.; Penttinen, T.; Veski, P.; Jürjenson, H.; Marvola, M. 2001: Time-controlled release pseudoephedrine tablets: bioavailability and in vitro/in vivo correlations Die Pharmazie 56(9): 718-723
Bekersky, I.; Poynor, W.J.; Colburn, W.A. 1980: Pharmacokinetics of saccharin in the rat. Renal clearance in vivo and in the isolated perfused kidney Drug Metabolism and Disposition: the Biological Fate of Chemicals 8(2): 64-67
Long, R.M.; Rickert, D.E. 1982: Metabolism and excretion of 2,6-dinitro [14C]toluene in vivo and in isolated perfused rat livers Drug Metabolism and Disposition: the Biological Fate of Chemicals 10(5): 455-458
Udo, U.F.; Ifon, E.T.; Umoh, I.B.; Eka, O.U. 1993: In vivo evaluation of iron bioavailability in some Nigerian peasant meals by haemoglobin regeneration technique Central African Journal of Medicine 39(7): 142-146
Sarr, M.G.; Bulkley, G.B.; Cameron, J.L. 1987: Temporal efficacy of allopurinol during the induction of pancreatitis in the ex vivo perfused canine pancreas Surgery 101(3): 342-346
Bekemeier, H.; Hänsel, F. 1988: Inflammation-induced vasodepression detected ex vivo in the isolated perfused hindlegs in mice Biomedica Biochimica Acta 47(9): 855-860
Cox, J.W.; Dring, L.G.; Ginsberg, L.C.; Larson, P.G.; Constable, D.A.; Ulrich, R.G. 1990: Distribution and disposition of trospectomycin sulfate in the in vivo rat, perfused rat liver, and cultured rat hepatocytes Drug Metabolism and Disposition: the Biological Fate of Chemicals 18(5): 726-731
Keyler, D.E.; Le Couteur, D.G.; Pond, S.M.; St Peter, J.V.; Pentel, P.R. 1995: Effects of specific antibody Fab fragments on desipramine pharmacokinetics in the rat in vivo and in the isolated, perfused liver Journal of Pharmacology and Experimental Therapeutics 272(3): 1117-1123