The effect of uropolinum on phagocytosis of sperm by cultured peritoneal macrophages in rats
Wenda-Rózewicka, L.; Mikulska, D.; Kurzawa, R.
Ginekologia Polska 67(8): 377-382
1996
ISSN/ISBN: 0017-0011 PMID: 9139003 Document Number: 465007
Peritoneal macrophages and sperm were cultured with and without uropolinum. The macrophages were isolated from female rat peritoneal cavities and sperm from male rat cauda epididymis. Sperm phagocytosis index was estimated in cultures with increasing concentrations of uropolinum. Authors concluded that uropolinum inhibited sperm phagocytosis by peritoneal macrophages. The results were verified by electron microscopic examinations. The latter additionally revealed that uropolinum enhanced an adhesion between the macrophages.