Association of postoperative brain dysfunction and atherosclerosis, intraoperative rSO2 and CO2 reaction in open heart surgery
Konishi, A.; Kikuchi, K.
Masui. Japanese Journal of Anesthesiology 45(3): 287-292
1996
ISSN/ISBN: 0021-4892 PMID: 8721125 Document Number: 464273
We studied the relationship between postoperative brain dysfunction and the state of atherosclerosis in the patients of open heart surgery, by analyzing the intraoperative cerebral oxygen saturation(rSo-2) and the CO-2 reaction. The subjects were 143 patients with average age of 64 years. The patients with low postoperative Hasegawa's Dementia Score were categorized as brain dysfunction group. rSo-2 was utilized to monitor cerebral blood flow, and AI and stiffness parameter beta were used for evaluation of systemic atherosclerosis. Postoperative brain dysfunction was confirmed in 12%. There were significantly high values of AI and beta as well as low rSo-2, in elder age with low cardiac index and no correlation was observed between rSo-2 and Pa-CO-2 in the brain dysfunction group. The results suggested that a higher level of atherosclerosis is associated with the postoperative brain dysfunction with resultant decreased cerebral blood flow and disturbed reaction to CO-2 of cerebral blood vessels.