Intraoperative plasmapheresis in patients undergoing CABG surgery; effect on intraoperative and postoperative homologous blood transfusion requirements
Hirose, Y.; Nishihama, M.; Takigawa, A.; Nakayama, K.
Masui. Japanese Journal of Anesthesiology 42(6): 936-939
1993
ISSN/ISBN: 0021-4892 PMID: 8320819 Document Number: 411091
To evaluate the effect of intraoperative plasmapheresis on intraoperative and postoperative homologous blood transfusion requirements, we assigned 89 patients undergoing primary CABG procedure to either the experimental group (plasmapheresis, n = 31, A group) or the control group (traditional method, n = 58, B group). All patients underwent hemodilution by withdrawal of autologous blood before cardiopulmonary bypass. In A group, the average volume withdrawn during plasmapheresis was approximately 948 ml (platelet rich plasma (PRP) and red blood cells). We removed an average of 751 ml of whole blood in B group. The percentage of patients without homologous blood transfusion in A group was 40% versus 32% in B group. The difference was not statistically significant. It was concluded that our method of plasmapheresis was effective in reducing homologous blood transfusion, but it was not more effective than the traditional hemodilution method.