Participation of inducible stress-proteins in realizing the cardioprotective effect of Rhodiolae rosea
Afanas'ev, S.A.; Krylatov, A.V.; Lasukova, T.V.; Lishmanov, I.V.
Biokhimiia 61(10): 1779-1784
1996
ISSN/ISBN: 0320-9725 PMID: 9011228 Document Number: 463776
The effects of the Rhodiolae rosea extract on contractility of rat hearts isolated by the Langendorff's technique, creatine phosphokinase activity in the perfusate, and induction of myocardial stress protein synthesis (hsp-70) were studied after total ischemia and reperfusion. The adaptogen produces cardioprotector effects and prevents ischemia- and reperfusion-induced contractility aberrations. The possible role of inducible stress proteins (hsp-70) in these effects is discussed.
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