Biological and clinical advances in stem cell expansion
Lange, W.; Henschler, R.; Mertelsmann, R.
Leukemia 10(6): 943-945
1996
ISSN/ISBN: 0887-6924 PMID: 8667649 Document Number: 462578
One of the most exciting areas of hematological research is the ex vivo expansion of peripheral blood progenitor cells (PBPC). Several groups clearly demonstrated that the ex vivo expansion of hematopoietic progenitor cells is possible in the presence of various cytokine combination and/or different feeder layer models. This minireview summarizes recent developments in ex vivo expansion systems as well as first clinical applications.
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