The relationship between in vitro and in vivo venous compliance measurement
Zamboni, P.; Marcellino, M.G.; Portaluppi, F.; Manfredini, R.; Feo, C.V.; Quaglio, D.; Liboni, A.
International Angiology a Journal of the International Union of Angiology 15(2): 149-152
1996
ISSN/ISBN: 0392-9590 PMID: 8803640 Document Number: 462386
Objective. To assess the relationship between in vitro and in vivo venous compliance measurement. Design. Prospective, blind study. Materials and methods. Patients affected by primary varicose veins and classified in accord with the new CEAP criteria (C-2-6/S, E-P, A-S1-4/p17-18, P-R) underwent blind venous compliance measurements using two different methods. 1) In vivo assessment of the compliance of the greater saphenous vein by duplex scanning, for diameter, and a needle transducer, for venous pressure measurements. 2) In vitro standard compliance assessment of the same vein segment after its excision. Results. The compliance values obtained with the two methods showed a significant degree of correlation, which improved with increasing intravenous pressures. Conclusions. In vivo compliance assessment of the saphenous vein was validated by the relationship with the standard in vitro measurement.