Scleroderma-polymyositis overlap syndrome associated with anti-Ku antibody and rimmed vacuole formation

Yamanishi, Y.; Maeda, H.; Katayama, S.; Ishioka, S.; Yamakido, M.

Journal of Rheumatology 23(11): 1991-1994

1996


ISSN/ISBN: 0315-162X
PMID: 8923381
Document Number: 462010
Scleroderma-polymyositis overlap syndrome is strongly associated with certain autoantibodies, such as anti-PM-Scl antibody and anti-Ku antibody. We describe a case of scleroderma-polymyositis overlap syndrome associated with anti-Ku antibody, which revealed rimmed vacuole formation in addition to intranuclear and intracytoplasmic filamentous inclusions in muscle biopsy specimens.

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