Improved single-step PCR assay for sex identification post-allogeneic sex-mismatched BMT

Pugatsch, T.; Oppenheim, A.; Slavin, S.

Bone Marrow Transplantation 17(2): 273-275

1996


ISSN/ISBN: 0268-3369
PMID: 8640178
Document Number: 459881
A method is presented which allows sex-identification simultaneously of both male and female cells in cell mixtures. The sensitivity of this PCR-based assay is one male cell in 10(6) female cells. The test can be used routinely to analyze bone marrow and peripheral blood lymphocytes post-allogeneic sex-mismatched bone marrow transplantation to detect early engraftment or rejection, as well as host cell regeneration.

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