Graft failure following neutrophil-specific alloantigen mismatched allogeneic BMT
Klumpp, T.R.; Herman, J.H.; Mangan, K.F.; Macdonald, J.S.
Bone Marrow Transplantation 11(3): 243-245
1993
ISSN/ISBN: 0268-3369 PMID: 8467290 Document Number: 408752
We report a case of unexplained graft failure in a 33-year-old man who received an allogeneic bone marrow graft that contained a donor-recipient mismatch involving the highly immunogenic NA1 neutrophil-specific alloantigen system. Laboratory and clinical data suggest that an alloimmune process related to the neutrophil alloantigen mismatch played a role in the development of the graft failure.
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