2 cases of frontal dementia with non-specific histological lesions: clinico-pathological and nosological discussion
Michel, B.; Didic, M.; Gambarelli, D.; Viallet, F.; Gastaut, J.L.
Revue Neurologique (Paris) 152(11): 669-677
1996
ISSN/ISBN: 0035-3787 PMID: 9033941 Document Number: 459260
We report two cases of mchlt frontal lobe dementia mchgt , patho-anatomically defined by non-specific as neuronal loss, gliosis and spongosis. The review of the literature permit to discuss the clinical picture of mchlt fronto-temporal dementia mchgt in regard to neuropathological basis. Further the boundaries with Pick's disease, Kraepelin disease, subcortical gliosis and the mchlt prions diseases mchgt are considered. Without more precise nosological status, tacking in count the great variability of the clinical signs, we can concluded that, at present time, the term of frontal type dementia with mchlt non-specific histological features mchgt that underlines the neuropathological characteristics is the most appropriate to define this clinico-pathological entity.