Colposcopy as a tool for detection of human papillomavirus infection of uterine cervix in the setting of high prevalence of gynaecologic infections
Singh, V.; Parashari, A.; Sodhani, P.; Chattopadhya, D.; Satyanarayana, L.; Gupta, M.M.; Sehgal, A.
Singapore Medical Journal 37(6): 588-590
1996
ISSN/ISBN: 0037-5675 PMID: 9104055 Document Number: 458465
A cross sectional study involving 257 women from the Maternal and Child Health Centre (MCH) in Delhi was initiated for screening clinically, cytologically, colposcopically, and microbiologically for several gynaecologic infections. Eighty percent of the women had one or more gynaecologic infections and 31.1% had three or more infections. Cytology revealed changes suggestive of condyloma in 3 (1.2%) women only, while colposcopic examination suggested HPV changes in 117 (45.50%) women. A very high proportion of colposcopically detected lesions (78.6%) had evidence of HPV related changes in histology. The specificity of these lesions were further confirmed by Pan HPV DNA in-situ hybridization, when 84% of the colposcopy is a valuable tool for detecting subclinical HPV lesions in a selfing with high prevalence of gynaecologic infections.