Imported cerebral malaria complicated with glucose-6-phosphate dehydrogenase deficiency
Chadee, D.D.; Tilluckdharry, C.C.; Doon, R.
West Indian Medical Journal 45(3): 97-99
1996
ISSN/ISBN: 0043-3144 PMID: 8952432 Document Number: 456954
Two cases of cerebral malaria imported from Guyana and Ghana are reported. These are the first cases of cerebral malaria diagnosed and treated in Trinidad and Tobago since malaria was eradicated. The management of both these cases was complicated because the patients' erythrocytes were glucose-6-phosphate dehydrogenase-deficient, and by the occurrence of blackwater fever, cerebral manifestations, renal impairment, hyperglycaemia and thrombocytopenia. The symptoms of cerebral malaria resolved following treatment with quinidine and doxycycline and quinidine and clindamycin.