Experimental study of the effect of formaldehyde during embryogenesis on the activity of rat liver enzyme systems in ontogenesis
Astakhova, L.F.; Mukhambetova, L.K.; Koganova, Z.I.; Dolinskaia, S.I.; Kazachkov, V.I.; Zhurkov, V.S.
Voprosy Meditsinskoi Khimii 42(3): 217-222
1996
ISSN/ISBN: 0042-8809 PMID: 9139453 Document Number: 456700
The pregnant rats were treated with formaldehyde (0.5 mg/kg daily per os) during whole period of pregnancy. The activity of cytochrome-c-oxidase, malate dehydrogenase, nucleotidase, glucose-6-phosphatase, beta-glucuronidase, N-acetyl-beta-glucosaminidase, beta-galactosidase, H(+)-ATPase, glutamate dehydrogenase, NAD- and NADP-isocitrate dehydrogenase, fructose-bisphosphate aldolase, glucose-6-phosphate dehydrogenase and content of protein in liver celts of offsprings (newborns, 2 weeks age and 2 months age) were studied. It was shown differences in development enzyme systems of control and experimental animals during ontogenesis.