The significance of lymph- and hemangiosis carcinomatosa in colorectal carcinoma

Schultheis, K.H.; Kosicki, C.; Ruckriegel, S.; Meyer, W.; Gebhardt, C.; Kaiser, A.; Wünsch, P.

Zentralblatt für Chirurgie 121(6): 442-449

1996


ISSN/ISBN: 0044-409X
PMID: 8767328
Document Number: 456545
Between 1.1.1988 and 31.12.1989 306 patients underwent curative surgery for colorectal cancer at the surgical center of Nurnberg City hospital. The pathohistological findings showed that a carcinomatous lymphangiosis and hemangiosis (LH+) was present in 57 (18.6%) cases. The rate of metachronic metastases of the liver was significantly higher (38.2% vs. 19.6% p < 0.001) compared to patients without lymphangiosis and hemangiosis (LH-). There were also significant differences between the survival rates (5-year survival rate 50% vs. 63% p < 0.02). Analysing the lymph node stage and LH+ situation it was found that carcinomatous lymphangiosis and hemangiosis were already present in 7.2% of patients who didn't have tumorous infiltration of the lymph nodes (p NO/LH+). The 5-year survival rate was bad in both groups (54% vs. 49%).

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