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Clinical significance of serum CA 125 values in patients with gastric cancers--especially correlation with peritonitis carcinomatosa

Takahashi, Y.; Suga, T.; Mai, M.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 19(7): 975-979

1992

ISSN/ISBN: 0385-0684
PMID: 1626954
Document Number: 398406
A study of 387 patients with gastric cancers revealed elevation of CA 125 in sera of 7.2% of the patients. Patients with Borrmann 1 and 2 in gross type, poorly differentiated adenocarcinoma in histological type and stage 4 in stage grouping of gastric cancer, showed a higher positive rate than patients with the others. In patients with peritonitis carcinomatosa, positive rate of serum CA 125 was 42.9% of patients with synclonus metastasis, 72.2% with metaclonus metastasis. Elevation of serum CA 125 was observed earlier than detection by image diagnosis in almost all cases. These results indicate that CA 125 is an useful tumor marker for detection and follow up of patients with peritonitis carcinomatosa from gastric cancers.

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