Treatment of HIV associated psoriatic arthritis with oral gold
Shapiro, D.L.; Masci, J.R.
Journal of Rheumatology 23(10): 1818-1820
1996
ISSN/ISBN: 0315-162X PMID: 8895167 Document Number: 455884
We report a patient with human immunodeficiency virus (HIV) infection and disabling psoriatic arthritis who was treated with auranofin. Her skin lesions and arthritis resolved after auranofin treatment and she has remained free of opportunistic infections during 24 mo followup. Her CD4 count during oral gold therapy showed a significant, sustained increase in CD4 cells. The literature on the effect of gold compounds on HIV infectivity and HIV reverse transcriptase is reviewed.