Cure of prophage in Staphylococcus aureus by furocoumarin photoadditions
Cavalcanti, S.M.; Siqueira Júnior, J.P.
Microbios 81(327): 85-91
1995
ISSN/ISBN: 0026-2633 PMID: 7476557 Document Number: 454046
In a previous report curing of prophage in Staphylococcus aureus by treatment with 8-methoxypsoralen plus near-UV (365 nm) radiation was described. In the present work the use of angelicin and 4,5',8-trimethylpsoralen and repeated irradiation show that monoadducts and DNA interstrand cross-links formed by furocoumarin photoaddition are involved in the curing of the prophage responsible for the suppression of the lipolytic activity in a putative repair proficient strain of Staphylococcus aureus.
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