Acute hepatitis A with coexistent hepatitis C virus infection presenting as a virus-associated hemophagocytic syndrome: a case report
Wu, C.S.; Chang, K.Y.; Dunn, P.; Lo, T.H.
American Journal of Gastroenterology 90(6): 1002-1005
1995
ISSN/ISBN: 0002-9270 PMID: 7771394 Document Number: 453893
A 23-yr-old mate with acute hepatitis A and coexistent hepatitis C became critically ill 3 wk after the onset of fever and jaundice with progressive anemia, thrombocytopenia, and hepatosplenomegaly. Bone marrow biopsy revealed hemophagocytosis. Despite aggressive supportive treatment with parenteral steroids, the patient died of disseminated intravascular coagulopathy with gastrointestinal bleeding. Necropsy of the liver showed histiocyte aggregation in the portal area with hemophagocytosis.
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