Bullous drug eruption to griseofulvin in a man with Hailey-Hailey disease
Meffert, J.J.; Davis, B.M.; Campbell, J.C.
Cutis 56(5): 279-280
1995
ISSN/ISBN: 0011-4162 PMID: 8565613 Document Number: 453557
Hailey-Hailey disease (chronic benign familial pemphigus) is a blistering disease characterized by episodic maceration and erosions in areas subject to friction and trauma such as the neck, axilla, and other intertriginous areas. We report a case in which a griseofulvin-induced drug eruption led to a generalized vesiculobullous eruption requiring treatment in a burn treatment center. This emphasizes that Hailey-Hailey disease, usually confined to relatively small areas, has the potential to cause blistering throughout the epidermis under certain conditions.