A mutable X (Z) -chromosome isolated from a natural population of Drosophila melanogaster

Iurchenko, N.N.; Zakharov, I.K.

Genetika 31(3): 422-426

1995


ISSN/ISBN: 0016-6758
PMID: 7607432
Document Number: 452664
In 1986, a mutable XZ-chromosome, in which mutation at genes yellow, white, and singed were recorded, was isolated from a natural population of Drosophila melanogaster from Zaporozh'e. Visible mutations in the region garnet-forked were also detected. Mutations appeared at a rate of about 10(-4) and were probably postmeiotic. Cytological analysis showed that two types of inversions occurred independently in XZ-chromosome. Specific features of this chromosome are hypermutability of the white locus (the mutation rate was approximately 10(-3) and a hot spot for chromosomal rearrangements in the terminal segment of the X-chromosome.

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