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Triacylglycerol composition of human endogenous lipoproteins

Lajos, S.; Katalin, R.; László, T.; Miklós, M.; István, K.; László, R.

Acta Bio-Medica de l'Ateneo Parmense 66(3-4): 153-159

1995

ISSN/ISBN: 0392-4203
PMID: 8578932
Document Number: 452275
The intact triacylglycerol profiles for VLDL and LDL of healthy and primary hypertriglyceridemic patients were obtained by high temperature capillary gas chromatography. The data were treated by the methods of computerized analysis. Marked individual heterogeneity was found. This can be explained by either genetic polymorphism or multiple lipoprotein triacylglycerol pools within one density class. Suspecting genetic polymorphism and determination type IV (familial hypertriglyceridemia) seems to be a pure overproduction of endogenous VLDL, while in type II B (familial combined hyperlipidemia) an altered mechanism of triacyglycerol synthesis can be supposed.

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