Resistance of Pseudomonas mallei to tetracyclines: assessment of the feasibility of chemotherapy
Manzeniuk, I.N.; Manzeniuk, O.I.; Filonov, A.V.; Stepanshin, I.G.; Svetoch, E.A.
Antibiotiki i Khimioterapiia 40(11-12): 40-44
1995
ISSN/ISBN: 0235-2990 PMID: 8830639 Document Number: 451396
The spectrum of cross resistance in tetracycline resistant strains of Pseudomonas mallei was studied. Possible use of antibacterial drugs in the prevention and treatment of mallel due to such strains was investigated in the experiments on golden hamsters and monkeys. It was shown that the efficacy of the minocycline therapy depended on the level of the strain resistance to tetracycline antibiotics. The combination of biseptol and ofloxacin proved to be highly efficient in the treatment of mallei.