A ten year clinical investigation of injectable contraceptives
Rustrian, A.
Investigacion Medica Internacional 7(1): 27-31
1980
ISSN/ISBN: 0185-2108 PMID: 12262411 Document Number: 451330
The article describes the results obtained over a period of 10 years with contraception by monthly injection of 150 mg of dihydroxyprogesterone acetophenide, and 10 mg of estradiol enanthate. 100 fertile patients were observed, for a total of 8074 cycles. There were no pregnancies, and only minimal side effects. No changes were observed in blood profile, urine and hepatic function, and in blood coagulation; there were no instances of breast or uterine cancer. In 10 years only 15% of patients abandoned this method because of changes in the menstrual cycle, changes which were expected, but which had not been explained to the patients.
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