Comparative clinical investigation of oral contraceptives with different doses
Mall-Haefeli, M.; Zodrow, I.W.; Uettwiller, A.
Geburtshilfe und Frauenheilkunde 39(7): 553-557
1979
ISSN/ISBN: 0016-5751 PMID: 467946 Document Number: 443670
The investigation of four oral contraceptives with different doses in adolescent girls showed that bleeding disturbances occur more frequently with low-dose preparations at the beginning of treatment. Nevertheless, these disturbances should be considered indicative of lesser central suppression. For this reason adolescent girls -- especially those with still immature cycles -- should be treated chiefly with preparations having only a low inhibitory effect on the central endocrine system in order not to disturb the maturation of the cycle.
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