Calcitriol analogs cause differentiation of neoplastic cells in culture
Srivastava, M.D.; Ambrus, J.L.; Uskokovic, M.R.
Research Communications in Molecular Pathology and Pharmacology 88(1): 79-85
1995
ISSN/ISBN: 1078-0297 PMID: 7620840 Document Number: 451038
Several investigators are developing calcitriol (DHCC, Compound A) derivatives which have less effect on mineral metabolism and are effective in causing differentiation of neoplastic cells. In the present study we investigated three new DHCC derivatives (Compounds B, C, D) for differentiation inducing effect in human neoplastic cell lines HL-60 and U-937.
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