Antigenic relationship between human IgE and canine IgE

Halliwell, R.E.; Schwartzman, R.M.; Rockey, J.H.

Clinical and Experimental Immunology 10(3): 399-407

1972


ISSN/ISBN: 0009-9104
PMID: 4624496
Document Number: 45052
Absorption of canine reaginic serum with anti-human IgE resulted in a substantial reduction in Prausntitz-Kustner titre to ragweed. Anti-human IgE was also effective in eliciting reversed cutaneous anaphylaxis in the dog. This is conclusive evidence of antigenic similarity of canine and human IgE. The immunolectrophoretic identification of canine IgE is described.

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