Induced expectoration: its role in the diagnosis of pneumocystis carinii pneumonia
Cabié, A.; Mendoza-Sassi, G.; Matheron, S.; Dombret, M.C.; Coulaud, J.P.
Presse Medicale 24(24): 1119-1120
1995
ISSN/ISBN: 0755-4982 PMID: 7567819 Document Number: 449368
The purpose of this retrospective study was to describe the changes and the effect of Pneumocystis carinii pneumonia (PCP) prophylaxis on induced sputum sensitivity during these five last years An induced sputum examination was performed in 80 cases of PCP over a 5-year period. The induced sputum were positive in 30 cases (sensitivity = 37.5%). This sensitivity changed very little during these five years. Thirty of these 80 patients (37.5%) received PCP prophylaxis at least for four weeks before PCP diagnosis. Induced sputum sensitivity was 50% in the group with prophylaxis versus 30% in the group without prophylaxis (p = 0.073). In our institution, the induced sputum examination remains an interesting diagnostic procedure for PCP. PCP prophylaxis does not seem to have effects on induced sputum sensitivity.