Mapping the sequences, preferentially bound with the nuclear matrix, on human chromosome 19

Nikolaev, L.G.; Tsogtkhishig, T.; Akopov, S.B.; Sverdlov, E.D.

Bioorganicheskaia Khimiia 21(12): 954-958

1995


ISSN/ISBN: 0132-3423
PMID: 8602892
Document Number: 448869
A plasmid library (400 clones) of the human chromosome 19 sequences selectively binding to nuclear matrix was obtained and characterized. Approximately 50% clones contained DNA sequences specific for human chromosome 19. Over 90% of these sequences represented matrix attachment regions (MARs). Eight MARs were localized to the chromosome 19 physical map.

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