The analysis of DNA amplified fragment length polymorphism in forensic identification expertise: the possible sources of errors under nonoptimal conditions for the polymerase chain reaction

Gyské, L.I.; Ivanov, P.L.

Sudebno-Meditsinskaia Ekspertiza 38(4): 12-17

1995


ISSN/ISBN: 0039-4521
PMID: 8848795
Document Number: 448813
Analyses the effects of nonoptimal conditions of polymerase chain reaction concerning the initial amount of matrix DNA and duration of its amplification on the amplification picture of hypervariable tandem-arranged locuses of human genome. Shows the causes of its possible ambiguous interpretation leading to inadequate expert conclusions in forensic gene-identification expert evaluation. Outlines the approaches to solution of this problem.

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