Therapeutic management of recurrent uterine cervix carcinoma following surgery alone or surgery with complementary endocavitary curietherapy
Basso Ricci, S.; Raspagliesi, F.
Minerva Ginecologica 47(10): 417-421
1995
ISSN/ISBN: 0026-4784 PMID: 8559431 Document Number: 448123
Sixty-eight cases of recurrence of cancer of the uterine neck, among which 8 after conization and 60 after Wertheim's enlarged hysterectomy, in a group of 472 patients are examined. No one of these 472 patients was subjected to external radiotherapy, because metastatic lymph nodes were not found at the time of the surgery of the primary tumor. The aim of the work was to examine the possibilities of identifying a subgroup of patients, among those without metastatic lymph nodes, for whom external radiotherapy, besides brachytherapy, could be considered useful on the basis of the extent of the primary tumor and of the histological type. Surgery has cured 11 patients; radiotherapy and radiochemotherapy possibly combined with surgery have cured 8 patients. Histological type and the extension of the tumor do not seem to influence the incidence of the relapses, however the authors opine that a multifactorial analysis, with includes other factors (HB rate, angiogenesis aneuploidism) could indicate a subgroup of patients for whom, in spite of absence of metastatic lymph nodes, could be concluded that the external precautional radiotherapy is useful.