The role of immunopathological factors in severe forms of insulin-dependent diabetes mellitus
Siplivyĭ, V.A.; Dikiĭ, I.L.; Beresnev, A.V.; Tikhonova, E.P.
Likars'ka Sprava 1995(3-4): 167-170
1995
ISSN/ISBN: 1019-5297 PMID: 8819957 Document Number: 445464
Immunogrammes of 31 patients with grave forms of insulindependent diabetes mellitus were reviewed. The illness has been characterized as a systemic immunopathologic process combining autoimmune and infectious-and-allergic components realized by organ and tissue abnormalities; it evolves against the manifest background of allergy of both delayed anl immediate types, impairement of the humoral and cell-mediated immunity function, pathogenetic activity of endogenous proteases, the complement system components and interferon.