Immune status and micro-hemodynamic function of patients with chronic alcoholism and liver pathology
Kut'ko, I.I.; Frolov, V.M.; Pustovoĭ, I.G.; Rachkauskas, G.S.
Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova 95(6): 63-66
1995
ISSN/ISBN: 1997-7298 PMID: 8788982 Document Number: 444995
126 patients with chronic alcoholism combined with hepatic pathology (of alcoholic genesis) were examined. Laboratory immunological observations with the using of monoclonal antibodies demonstrated the expressed alterations of immune homeostasis exactly the decrease of total T-lymphocytes population (CD11+) as well as the number of T-helpers/inductors (CD40, immunoregulatory index and the increase of the level of circulating immune complexes. The correlation between the immune alterations and the microhemodynamic disturbances was also observed. In connection with the results mentioned above the question arose about application worth of both immunological correctors and angioprotectors in therapy of alcoholism espessially combined with hepatic pathology.