A comparative examination of the hemostatic properties of xenogenic collagenic biomaterials
Antiszko, M.; Braczko, M.; Grzybowski, J.; Jethon, J.
Polimery W Medycynie 25(3-4): 37-45
1995
ISSN/ISBN: 0370-0747 PMID: 8610065 Document Number: 444728
The results of haemostatic properties examination of bovine collagen membranes and sponges manufactured in Poland in comparison to Spongostan are presented. In the first step of investigation the experiments were performed using punctured mouse livers. The second step comprised clinical trials in seven patients hospitalised in the Department of Plastic Surgery. The estimated parameter was the time of parenchymal bleeding from punctured livers of from donor places after cutting of the skin for split thickness grafts. The application of tested collagenic membranes or sponges caused effective decreasing of bleeding time. They are potent agents in the cases of abundant capillary bleeding of parenchymal organs and cutaneous tissues. The efficacy of hemostasis initiated by collagen membranes was the same as for Spongostan. The highest haemostatic potency possessed collagenic sponge.