Glutathion S-transferase activity and DDT-susceptibility of Malaysian mosquitos

Lee, H.L.; Chong, W.L.

Southeast Asian Journal of Tropical Medicine and Public Health 26(1): 164-167

1995


ISSN/ISBN: 0125-1562
PMID: 8525405
Document Number: 444162
Comparative DDT-susceptibility status and glutathion s-transferase (GST) activity of Malaysian Anopheles maculatus, Culex quinquefasciatus and Aedes aegypti was investigated to ascertain the role of this enzyme in DDT resistance. The standardised WHO dose-mortality bioassay tests were used to determine DDT susceptibility in these mosquitos, whilst GST microassay (Brogdon and Barber, 1990) was conducted to measure the activity of this enzyme in mosquito homogenate. It appeared that DDT susceptibility status of Malaysian mosquitos was not correlated with GST activity.

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