Peritoneal papillary serous carcinoma: response to Taxol in platinum resistant disease
Wilailak, S.; Kudelka, A.P.; Donner, L.R.; Silva, E.; Mante, R.; Kavanagh, J.J.
European Journal of Gynaecological Oncology 16(3): 187-189
1995
ISSN/ISBN: 0392-2936 PMID: 7664764 Document Number: 443047
A case of peritoneal papillary serous carcinoma which developed after total abdominal hysterectomy and bilateral salpingo-oophorectomy for a benign condition is presented. The patient was treated with platinum-based chemotherapy to which she initially responded, but then the tumor progressed. High dose paclitaxel (250 mg/m-2) was given. The patient tolerated this treatment well, achieving a rapid partial response with good palliation of symptoms. Paclitaxel should be considered for patients with a platinum resistant peritoneal papillary serous carcinoma.