Optimal use of non opioid analgesics
Fletcher, D.
Cahiers d'Anesthesiologie 43(3): 239-249
1995
ISSN/ISBN: 0007-9685 PMID: 7583888 Document Number: 441014
This review describes the mechanisms of analgesic effect, advantages and risks related to the perioperative use of non steroidal antiinflammatory drugs (NSAID's). The NSAID's should be used as the first analgesic, around the clock, with a rapid onset of the therapy. Their combination with other NSAID's (acetaminophen) or opioids can have an additive analgesic effect and may limit frequent secondary effects as nausea and vomiting. Their potential toxicity must be remembered and the contra indications, maximum doses and duration of treatment have to be respected.